Lesson 1Infectious disease evaluation: latent infections (TB, CMV, EBV, VZV, HBV, HCV, HIV), vaccination review, prophylaxis planningCovers infection checks for transplant patients, focusing on hidden infections like TB, vaccination status, and custom prevention plans to cut down post-transplant infections and reactivation due to immune suppression.
Screening for TB, CMV, EBV, and VZVHBV, HCV, and HIV testing and stagingPre‑transplant vaccination catch‑up planDonor‑recipient serostatus risk matchingDesigning antiviral and PCP prophylaxisLesson 2Cardiology workup: noninvasive ischemia testing, coronary angiography indications, functional capacity assessment, perioperative revascularization criteriaDiscusses heart checks for transplant candidates, including non-invasive tests for blocked arteries, when to do coronary angiography, fitness evaluation, and criteria for fixing blockages to lower heart risks during surgery.
Baseline ECG and echocardiographyStress testing and ischemia detectionIndications for coronary angiographyFunctional capacity and METs assessmentRevascularization versus medical therapyLesson 3Endocrine and metabolic optimization: diabetes control strategies pre-transplant, obesity and nutritional optimization, weight-loss options and timelineLooks at hormone and metabolism issues before kidney transplant, stressing diabetes control, weight and diet improvement, weight-loss methods, and practical timelines to meet targets that reduce surgery and long-term issues.
Pre‑transplant HbA1c and glycemic targetsAdjusting insulin and non‑insulin therapiesObesity‑related surgical and graft risksNutritional assessment and protein‑energy statusPharmacologic and surgical weight‑loss optionsLesson 4Laboratory and imaging baseline tests: crossmatch/serology, HLA typing, PRA, baseline renal ultrasound and vascular imaging, baseline BK/JC viral statusLists key lab and scan tests for pre-transplant baseline, like HLA typing, PRA, crossmatch, blood tests, kidney ultrasound, vessel imaging, and BK/JC virus status to help pick donors and plan surgery.
ABO typing, HLA typing, and PRA levelsComplement‑dependent and flow crossmatchBaseline renal ultrasound and DopplerCT or MR angiography of iliac vesselsBK and JC virus PCR and serologic statusLesson 5Decision criteria to accept or delay transplant: cardiopulmonary thresholds, infection control, vascular access/target vessel suitability, BMI and metabolic targetsExplains how teams decide to go ahead or wait for kidney transplant, weighing heart-lung limits, infection control, vessel fitness, BMI, and metabolism goals to balance need with fixable risks.
Cardiopulmonary fitness and VO2 thresholdsActive infection and sepsis exclusionTarget vessel imaging and suitabilityBMI cutoffs and weight‑loss milestonesMetabolic syndrome and blood pressure goalsLesson 6Pulmonary evaluation and anesthesia risk: spirometry, sleep apnea screening, frailty and functional status assessmentDescribes lung and anaesthesia risk checks, including breathing tests, sleep apnoea screening, weakness, and daily function assessment to gauge surgery risks and plan improvements and monitoring.
History, exam, and spirometry indicationsChest imaging and pulmonary hypertensionScreening and management of sleep apneaFrailty indices and gait speed testingAnesthesia risk classification and planningLesson 7Vascular surgery assessment: peripheral arterial disease mapping, iliac/femoral vessel duplex/CT angiography, access site planningExamines vessel surgery checks for kidney transplant, mapping artery disease in limbs, scanning iliac and femoral vessels, and picking best entry points for safe joining and lasting blood flow.
Clinical exam for peripheral arterial diseaseDuplex ultrasound of iliac and femoral vesselsCT angiography for complex vasculatureChoosing side and site for graft anastomosisManaging severe aortoiliac occlusive diseaseLesson 8Hematology and coagulation: platelet function, anticoagulation/antiplatelet management, transfusion thresholdsFocuses on blood and clotting checks, covering low blood count, platelet work, handling blood thinners, and transfusion limits to cut bleeding and clotting risks around surgery.
Baseline CBC, iron studies, and anemia planPlatelet count, function, and uremic bleedingWarfarin, DOAC, and heparin bridgingAntiplatelet interruption and continuationRed cell and platelet transfusion thresholdsLesson 9Psychosocial and adherence assessment: evaluation of social support, substance use, medication adherence predictorsDeals with mental-social checks before transplant, including family support, mental health, addictions, and medicine-taking patterns to spot hurdles and plan fixes for better graft life.
Standardized psychosocial screening toolsEvaluating caregiver and social supportScreening for depression and anxietySubstance use history and toxicology testsPredictors and remediation of nonadherenceLesson 10Comprehensive medical history and physical exam: diabetes, cardiovascular, peripheral vascular disease, dialysis access reviewOutlines full pre-transplant history and exam, highlighting heart, vessel, diabetes, and dialysis access review to find blocks and fixable surgery risks.
Structured transplant‑focused historyCardiovascular and peripheral vascular reviewDiabetes complications and foot examinationDialysis access function and infection historyMedication reconciliation and allergy review
