Lesson 1Pathophysiology of sepsis and septic shock: host response, organ dysfunction, and progressionDescribes the body's reaction to infection, covering swelling and defence pathways, small blood vessel problems, and cell failures. Connects these to organ damage, shock worsening, and signs that nurses watch closely during patient care.
Body's defence reaction to infection in sepsisDamage to blood vessel linings and fluid leakageProblems in small blood vessels and cell energy centresProgression from sepsis to septic shock: main changesPatterns of organ failure and SOFA scoring ideasClinical signs linked to disease processesLesson 2Fluid therapy specifics: crystalloid selection, bolus strategies, and recognition of fluid overloadDiscusses choice of salt solutions, amounts and speeds for early sepsis treatment. Stresses checking fluid response dynamically, spotting overload at bedside, and nurse methods to maintain blood flow while avoiding damage.
Balanced salt solutions versus normal saline choicesStarting fluid amounts and recheck timingsFixed and changing fluid response methodsBedside signs of too much fluidRecording fluid balance and overall statusTeamwork on reducing fluid strategiesLesson 3Patient safety and sepsis-related complications: acute kidney injury, coagulopathy, and need for organ supportCovers usual sepsis issues like sudden kidney damage, blood clotting problems, breathing failure, and need for organ help. Focuses on early spotting, prevention steps, and nurse care for kidney, lung, and blood support.
Spotting and grading sudden kidney damageBlood clotting issues, widespread clotting, and bleeding dangersBreathing failure and machine breathing supportBlood flow support beyond pressure drugsNurse care for kidney machine therapyStopping and early finding of problemsLesson 4Documentation and communication: recording bundle elements, escalation triggers, and handover of sepsis careExplains precise recording of sepsis care packages, vital sign changes, and treatments, plus clear sharing of alert points. Stresses organised handovers, loop-back talks, and lists to keep care flowing smoothly.
Noting sepsis care package parts and timesRecording blood flow and lactate changesAlert points and quick response standardsOrganised handover methods for sepsis patientsTeam talk best waysLegal and quality effects of recordsLesson 5Antimicrobial stewardship and timing: empirical therapy selection, de-escalation, and culture stewardshipEmphasises quick choice, dosing, and giving of initial germ-killing drugs in sepsis. Reviews taking samples, rechecking with new info, reducing drugs, and nurse parts in wise drug use and watching side effects.
Timing of first germ-killing drug dose in sepsisInitial treatment choice and local germ patternsTaking samples without delaying treatmentReducing and length of treatmentWatching for drug side effectsNurse roles in wise drug meetingsLesson 6Vasopressors and inotropes: indications, dosing targets, titration, adverse effects, and common nurse-driven protocols for norepinephrineExamines norepinephrine as main pressure drug in septic shock, covering when to use, starting doses, adjustment steps, monitoring goals, side effects, and usual nurse-led plans, including safety and line checks.
When to use norepinephrine in septic shockStarting doses, strength, and adjustment stepsBlood pressure goals and flow monitoringSpotting and handling side effectsCentral line use, keeping open, and leak careNurse-led pressure drug adjustment plansLesson 7Current international sepsis guidelines and bundles (Surviving Sepsis Campaign): 1‑hour and 3‑hour elementsSummarises latest Surviving Sepsis Campaign rules and care packages, focusing on 1-hour and 3-hour parts. Highlights time-critical nurse actions, local plan changes, and review processes to boost following rules and patient results.
Main ideas of Surviving Sepsis CampaignOne-hour care package parts and nurse actionsThree-hour care package parts and orderFitting care packages into unit routinesChecking following and feedback loopsChanging rules to local meansLesson 8Hemodynamic goals in sepsis: MAP targets, lactate-guided resuscitation, and fluid responsiveness assessmentSets blood flow goals in sepsis, like blood pressure aims, lactate reduction, and flow signs. Reviews bedside fluid response checks and using changing measures, scans, and judgement in treatment choices.
Blood pressure aims and personal goalsLactate changes and flow-led treatmentCapillary refill and edge flow signsChanging measures for fluid responseBedside scan role in volume checksBalancing fluids, pressure drugs, and heart drugsLesson 9Monitoring response to sepsis treatment: serial lactates, urine output, end-organ perfusion markers, and bedside clinical toolsExplains tracking sepsis treatment response with repeated lactates, urine amounts, mind state, and organ signs. Covers bedside tools, recheck frequency, and records to guide continued treatment and reduction.
Repeated lactate checks and meaningsUrine amount goals and kidney flowBrain state and confusion checksSkin, heat, and flow checksRecheck round frequency and setupChange-based records and care changesLesson 10Infection source control: principles, timelines, and nursing coordination for procedures and diagnosticsOutlines infection source control basics, including timing, arranging scans and steps, and team talks. Highlights nurse roles in readying, moving, consent help, and after-step watching.
Finding likely infection sources earlyTiming and need for source control stepsArranging scans and bedside stepsBefore-step readying and safety checksAfter-step watching and problem signsNurse role in team planning
