Lesson 1Infectious disease evaluation: latent infections (TB, CMV, EBV, VZV, HBV, HCV, HIV), vaccination review, prophylaxis planningCovers infection checks for transplant patients, focusing on hidden infections common here like TB, vaccination status, and custom prevention plans to cut down opportunistic infections after transplant under immune suppression.
Screening for TB, CMV, EBV, and VZVHBV, HCV, and HIV testing and stagingPre‑transplant vaccination catch‑up planDonor‑recipient serostatus risk matchingDesigning antiviral and PCP prophylaxisLesson 2Cardiology workup: noninvasive ischemia testing, coronary angiography indications, functional capacity assessment, perioperative revascularization criteriaLooks at heart checks for transplant candidates, including non-invasive tests for blocked arteries, when to do heart scans, fitness levels, and criteria for fixing blockages to lower heart risks during surgery.
Baseline ECG and echocardiographyStress testing and ischemia detectionIndications for coronary angiographyFunctional capacity and METs assessmentRevascularization versus medical therapyLesson 3Endocrine and metabolic optimization: diabetes control strategies pre-transplant, obesity and nutritional optimization, weight-loss options and timelineReviews hormone and metabolism issues before kidney transplant, stressing diabetes management, tackling obesity and nutrition, weight loss methods, and practical timelines to hit targets that reduce surgery and long-term problems.
Pre‑transplant HbA1c and glycemic targetsAdjusting insulin and non‑insulin therapiesObesity‑related surgical and graft risksNutritional assessment and protein‑energy statusPharmacologic and surgical weight‑loss optionsLesson 4Laboratory and imaging baseline tests: crossmatch/serology, HLA typing, PRA, baseline renal ultrasound and vascular imaging, baseline BK/JC viral statusOutlines key lab and scan tests setting the pre-transplant baseline, like tissue matching, antibody levels, blood tests, kidney scans, vessel imaging, and virus checks to guide donor choice and surgery plans.
ABO typing, HLA typing, and PRA levelsComplement‑dependent and flow crossmatchBaseline renal ultrasound and DopplerCT or MR angiography of iliac vesselsBK and JC virus PCR and serologic statusLesson 5Decision criteria to accept or delay transplant: cardiopulmonary thresholds, infection control, vascular access/target vessel suitability, BMI and metabolic targetsExplains how teams decide to go ahead or hold off on kidney transplant, weighing heart-lung limits, infection clearance, vessel fitness, and body weight goals to match urgency with fixable risks.
Cardiopulmonary fitness and VO2 thresholdsActive infection and sepsis exclusionTarget vessel imaging and suitabilityBMI cutoffs and weight‑loss milestonesMetabolic syndrome and blood pressure goalsLesson 6Pulmonary evaluation and anesthesia risk: spirometry, sleep apnea screening, frailty and functional status assessmentDescribes lung and anaesthesia risk checks, including breathing tests, sleep apnoea screening, weakness levels, and daily function to gauge surgery risks and plan improvements, monitoring, and aftercare.
History, exam, and spirometry indicationsChest imaging and pulmonary hypertensionScreening and management of sleep apneaFrailty indices and gait speed testingAnesthesia risk classification and planningLesson 7Vascular surgery assessment: peripheral arterial disease mapping, iliac/femoral vessel duplex/CT angiography, access site planningLooks at vessel surgery checks for kidney transplant plans, mapping leg artery issues, scanning hip and thigh vessels, and picking best entry points for safe joining and lasting blood flow.
Clinical exam for peripheral arterial diseaseDuplex ultrasound of iliac and femoral vesselsCT angiography for complex vasculatureChoosing side and site for graft anastomosisManaging severe aortoiliac occlusive diseaseLesson 8Hematology and coagulation: platelet function, anticoagulation/antiplatelet management, transfusion thresholdsFocuses on blood and clotting checks, covering low blood counts, platelet work, blood thinner handling, to set transfusion limits and cut bleeding or clotting risks around surgery.
Baseline CBC, iron studies, and anemia planPlatelet count, function, and uremic bleedingWarfarin, DOAC, and heparin bridgingAntiplatelet interruption and continuationRed cell and platelet transfusion thresholdsLesson 9Psychosocial and adherence assessment: evaluation of social support, substance use, medication adherence predictorsCovers planned social and mental health checks before transplant, including family support, mental wellbeing, substance habits, and medicine-taking patterns to spot barriers and plan interventions for better graft life.
Standardized psychosocial screening toolsEvaluating caregiver and social supportScreening for depression and anxietySubstance use history and toxicology testsPredictors and remediation of nonadherenceLesson 10Comprehensive medical history and physical exam: diabetes, cardiovascular, peripheral vascular disease, dialysis access reviewSums up the full pre-transplant history and exam structure, highlighting heart, leg vessels, diabetes, and dialysis line checks to find no-go factors and fixable surgery risks.
Structured transplant‑focused historyCardiovascular and peripheral vascular reviewDiabetes complications and foot examinationDialysis access function and infection historyMedication reconciliation and allergy review
