Lesson 1Milling and sieving equipment: oscillating mills, conical mill, hammer mill, sieves — particle size targets and feed controlReviews shaking, cone, hammer mills plus sieving systems. Stresses particle size goals, screen pick, feed control, heat make, metal control for even granule features and later work.
Shaking mill work and usesCone mill design and screen picksHammer mill hit and heat controlSieving systems and mesh pickFeed rate, separate, metal checksLesson 2Granulation equipment: high-shear granulator, oscillating granulator, twin-screw granulator — process overview and when to useDetails high-shear, shaking, twin-screw granulators, comparing ways, process parts, scale-up. Discusses binder add, end spot, criteria for tool pick based on mix and wanted granule features.
High-shear granulator design and controlShaking granulator uses and limitsTwin-screw wet granulation basicsBinder add and end spotPick granulation route for productLesson 3Primary packaging equipment: blister machines, bottle filling, capping — selection based on product and marketLooks at blister, bottle fill, cap lines, focusing tool pick by product feel, stability, market needs. Deals line setup, change, during checks, pack strong test needs.
Blister machine types and key partsBottle fill line design and controlCap systems and torque checkPack pick by product stabilityDuring checks and pack strongLesson 4Drying equipment: tray dryer vs fluid bed dryer — drying kinetics, typical parameters and monitoringCompares tray and fluid bed dryers, covering drying speed, heat mass move, usual process parts. Discusses end spot, sampling, controls to avoid breakdown, hard case, uneven moisture.
Tray dryer air flow and load patternsFluid bed dryer design and air moveDrying speed and key moistureUsual temp and air flow rangesMoisture end tests and samplingLesson 5Lubrication and final blending equipment: tumble blender, low-shear blending best practices to avoid over-lubricationExplores lubrication and last mix tools, stressing tumble and low-shear mixers. Covers lubricant pick, add order, mix time, sampling, controls to stop too much lubrication and even mix.
Tumble mixer design and work partsLow-shear mix and scale-up worriesAdd order and lubricant spreadSpot and stop too much lubricationDuring controls for last mix qualityLesson 6Weighing and dispensing: floor/bench scales, electronic balance calibration, batch reconciliation and checksFocuses on weighing and giving out work, including floor bench scales, balance check, area effects. Explains material ID, line clear, batch match, paperwork for GMP keep.
Scale pick and setup checksBalance check and trueArea effects on weighingMaterial ID, tags and line clearBatch match and difference handleLesson 7Compression and tooling: rotary tablet press basics, turret speed, fill depth, tooling selection and punch maintenanceCovers rotary tablet press build, turret speed, fill depth, hold time. Explains tool types, punch tip design, keep practices to stop faults, less wear, even tablet quality output.
Rotary tablet press parts and jobsTurret speed, hold time outputDie fill depth weight controlTool pick and punch tip designPunch check, clean keepLesson 8Coating equipment fundamentals: pan coating basics vs perforated pan and rationale for optional film coatingIntroduces coating pans perforated pans, spray break, drying areas. Explains film coating mix, process parts, when coating optional for stability, taste hide, ID, changed release.
Usual vs perforated coating pansSpray guns, break droplet sizeBed temp exhaust controlFilm coating mix partsReasons apply or skip coatingLesson 9Blending equipment: V-blender, bin blender, high-shear mixer — operating principles and suitabilityDescribes V-blenders, bin blenders, high-shear mixers, comparing mix ways, scale-up, mix even test. Guides tool pick based on powder flow, density, separate risk for strong mix processes.
V-blender shape mix patternsBin blender in closed handleHigh-shear mixer for sticky powdersMix even sampling plansPick mixers by powder featuresLesson 10Raw material receipt, sampling and storage equipment: sacks, drums, sampling thief, controlled storage conditions, documentationDeals raw material get, sampling, store tools, including bags, drums, sampling tools, controlled areas. Covers tags, status control, paperwork, separate for track keep, stop mix-ups.
Get checks container checkSampling plans thief use controlsStore conditions monitorTags, status tags quarantinePaperwork, track audits
