Structural Biochemistry Course
Master protein-DNA recognition in this Structural Biochemistry Course. Gain skills in key DNA-binding domains, analysing PDB complexes, predicting mutational effects, and transforming structural data into actionable insights for biological research and drug discovery in a South African context.

from 4 to 360h flexible workload
certificate valid in your country
What will I learn?
This Structural Biochemistry Course equips you with practical skills to analyse protein-DNA interactions confidently. Delve into DNA-binding domains, recognition modes, and structural biology basics, then master PDB, PyMOL, Chimera, and essential servers to interpret complexes, predict mutation impacts, compare interfaces, and create clear, evidence-based structural reports for informed research decisions.
Elevify advantages
Develop skills
- Analyse protein-DNA interfaces: map grooves, contacts, and key residues quickly.
- Utilise PyMOL, Chimera, and PDB tools to inspect, compare, and validate complexes.
- Predict mutation effects on DNA binding using FoldX, Rosetta, and MD insights.
- Interpret DNA-binding motifs and recognition modes for sequence and shape readout.
- Build clear, data-backed structural reports linking 3D changes to function.
Suggested summary
Before starting, you can change the chapters and the workload. Choose which chapter to start with. Add or remove chapters. Increase or decrease the course workload.What our students say
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