Crystallization Course
This course equips you with practical tools to master crystallization of organic APIs. You will learn solvent selection, seeding techniques, cooling profiles, PAT implementation, and reliable scale-up strategies. Design robust processes that precisely control crystal size, polymorphs, filtration, and drying to ensure consistent, high-quality batches every time.

from 4 to 360h flexible workload
valid certificate in your country
What will I learn?
Gain practical tools for designing robust crystallization processes for organic APIs. Master polymorphism, solubility, supersaturation, cooling profiles, seeding, and solvent choice. Explore mixing, hydrodynamics, PAT, and data-driven controls to shape crystal size, filtration, drying, and batch consistency, with guidance on experiments, risk assessment, and scale-up.
Elevify advantages
Develop skills
- Design crystallization processes by tuning solubility, supersaturation, and crystal habit quickly.
- Engineer crystal size through optimized cooling, seeding, and mixing for tight particle size distribution.
- Control polymorphs by managing solvents, antisolvents, and solid form risks effectively.
- Apply PAT tools like FBRM, turbidity, and spectroscopy for real-time process control.
- Scale up robustly by linking lab DoE, hydrodynamics, and risk analysis to plant operations.
Suggested summary
Before starting, you can change the chapters and the workload. Choose which chapter to start with. Add or remove chapters. Increase or decrease the course workload.What our students say
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