Genetic Mutations Course
Gain mastery over genetic mutations in colorectal cancer through this focused course. Explore critical driver genes including APC, KRAS, TP53, and MMR pathways. Develop skills to classify variants like missense, truncating, and VUS, integrate tumor and germline testing data such as MSI and IHC, leverage genomic databases like ClinVar, COSMIC, cBioPortal, and gnomAD, and create clear reports that inform oncology teams and support precise clinical and research decisions.

from 4 to 360h flexible workload
valid certificate in your country
What will I learn?
This course offers a practical overview of colorectal cancer genetics, covering key pathways, driver genes like APC, KRAS, TP53, and MMR, variant types, and their clinical relevance. You will learn to interpret missense, truncating, and VUS findings, integrate tumor and germline data, utilize major variant databases such as COSMIC and ClinVar, and produce actionable reports to guide therapy selection and clinical decisions.
Elevify advantages
Develop skills
- Interpret cancer variants confidently by classifying missense, truncating, and VUS findings.
- Analyze colorectal cancer pathways linking APC, KRAS, TP53, and MMR changes to disease progression.
- Utilize tumor and germline tests including MSI, IHC, and sequencing to determine mutation status.
- Access and apply genomic databases like COSMIC, ClinVar, cBioPortal, and gnomAD for variant annotation.
- Translate genetic mutations into clinical care by preparing clear, actionable reports for oncology teams.
Suggested summary
Before starting, you can change the chapters and the workload. Choose which chapter to start with. Add or remove chapters. Increase or decrease the course workload.What our students say
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