Lesson 1Infectious disease evaluation: latent infections (TB, CMV, EBV, VZV, HBV, HCV, HIV), vaccination review, prophylaxis planningThis lesson covers checking for hidden infections in people waiting for transplant, looking at shots they've had, and making plans to stop sickness after transplant when medicines weaken the body.
Screening for TB, CMV, EBV, and VZVHBV, HCV, and HIV testing and stagingPre‑transplant vaccination catch‑up planDonor‑recipient serostatus risk matchingDesigning antiviral and PCP prophylaxisLesson 2Cardiology workup: noninvasive ischemia testing, coronary angiography indications, functional capacity assessment, perioperative revascularization criteriaThis covers heart checks for transplant patients, tests without cutting, when to do heart vessel scans, how well they move, and rules for fixing heart vessels to avoid heart problems during surgery.
Baseline ECG and echocardiographyStress testing and ischemia detectionIndications for coronary angiographyFunctional capacity and METs assessmentRevascularization versus medical therapyLesson 3Endocrine and metabolic optimization: diabetes control strategies pre-transplant, obesity and nutritional optimization, weight-loss options and timelineThis reviews body balance issues before kidney transplant, focusing on sugar sickness control, too much weight and food plans, ways to lose weight, and real times to meet goals that cut surgery and long problems.
Pre‑transplant HbA1c and glycemic targetsAdjusting insulin and non‑insulin therapiesObesity‑related surgical and graft risksNutritional assessment and protein‑energy statusPharmacologic and surgical weight‑loss optionsLesson 4Laboratory and imaging baseline tests: crossmatch/serology, HLA typing, PRA, baseline renal ultrasound and vascular imaging, baseline BK/JC viral statusThis lists key blood and scan tests before transplant, like body match checks, PRA, blood tests, kidney scans, vessel pictures, and virus checks to pick the right giver and plan surgery.
ABO typing, HLA typing, and PRA levelsComplement‑dependent and flow crossmatchBaseline renal ultrasound and DopplerCT or MR angiography of iliac vesselsBK and JC virus PCR and serologic statusLesson 5Decision criteria to accept or delay transplant: cardiopulmonary thresholds, infection control, vascular access/target vessel suitability, BMI and metabolic targetsThis explains how teams decide to do or wait on kidney transplant, mixing heart-lung limits, stopping infections, vessel fit, body weight, and health goals to match need with fixable risks.
Cardiopulmonary fitness and VO2 thresholdsActive infection and sepsis exclusionTarget vessel imaging and suitabilityBMI cutoffs and weight‑loss milestonesMetabolic syndrome and blood pressure goalsLesson 6Pulmonary evaluation and anesthesia risk: spirometry, sleep apnea screening, frailty and functional status assessmentThis describes lung and sleep checks for surgery risk, breath tests, sleep stop checks, weakness, and daily ability to guess surgery danger and plan fixes, watching, and after-care.
History, exam, and spirometry indicationsChest imaging and pulmonary hypertensionScreening and management of sleep apneaFrailty indices and gait speed testingAnesthesia risk classification and planningLesson 7Vascular surgery assessment: peripheral arterial disease mapping, iliac/femoral vessel duplex/CT angiography, access site planningThis looks at vessel checks for kidney transplant, mapping leg vessel problems, scanning hip and leg vessels, picking best spots for safe joining and long kidney blood flow.
Clinical exam for peripheral arterial diseaseDuplex ultrasound of iliac and femoral vesselsCT angiography for complex vasculatureChoosing side and site for graft anastomosisManaging severe aortoiliac occlusive diseaseLesson 8Hematology and coagulation: platelet function, anticoagulation/antiplatelet management, transfusion thresholdsThis focuses on blood and clotting checks, low red cells, platelet work, handling blood thinners, setting blood give limits to cut bleeding and clots around surgery.
Baseline CBC, iron studies, and anemia planPlatelet count, function, and uremic bleedingWarfarin, DOAC, and heparin bridgingAntiplatelet interruption and continuationRed cell and platelet transfusion thresholdsLesson 9Psychosocial and adherence assessment: evaluation of social support, substance use, medication adherence predictorsThis covers mind and social checks before transplant, family help, mind health, bad habits, medicine follow signs to find blocks and make plans for better kidney life.
Standardized psychosocial screening toolsEvaluating caregiver and social supportScreening for depression and anxietySubstance use history and toxicology testsPredictors and remediation of nonadherenceLesson 10Comprehensive medical history and physical exam: diabetes, cardiovascular, peripheral vascular disease, dialysis access reviewThis sums up full health story and body check before transplant, stressing heart, leg vessels, sugar sickness, dialysis line review to find no-go's and fixable surgery risks.
Structured transplant‑focused historyCardiovascular and peripheral vascular reviewDiabetes complications and foot examinationDialysis access function and infection historyMedication reconciliation and allergy review
