Lesson 1Compounding procedures for oral liquids: wetting, triturating, levigating, and homogenization techniques; equipment and in‑process controlsThis part describes step-by-step making of kids' oral liquids, including math, grinding, wetting, smoothing, thinning, mixing even, filtering, and checks during to ensure evenness, lasting, and no germs.
Pre-compounding checks and calculationsTrituration, wetting, and levigation stepsOrder of mixing and volume make-upHomogenization and de-aeration methodsIn-process controls and documentationLesson 2Stability, beyond‑use dating, storage, and transport for pediatric liquids; container selection and oral dosing devicesThis part details what keeps kids' liquids good, like breakdown paths, germ dangers, use-by dates, and how containers, tops, storage, moving affect quality, safety, and right doses.
Degradation pathways in aqueous preparationsMicrobial growth risks and preservative needsAssigning evidence-based beyond-use datesContainer and closure selection criteriaStorage, transport, and temperature controlLesson 3Selection of dosage form: solution vs suspension vs syrup — advantages and limitationsThis part compares clear liquids, shakes, and sweet syrups for kids, listing good points, limits, and choices based on drug traits, dose ease, lasting, taste, and error risks.
Characteristics of oral solutionsCharacteristics of oral suspensionsCharacteristics of syrups and elixirsComparing stability and dose uniformityChoosing dosage form for specific APIsLesson 4Clinical considerations for pediatric patients: dosing by weight, formulation acceptability, and administration aidsThis part looks at clinic needs for kids' oral liquids, like weight doses, right amounts by age, if they like it, help tools, and ways to help them take it right and avoid mistakes.
Weight- and BSA-based dose calculationsAge-appropriate dosing volumesAssessing taste and texture acceptabilityAdministration aids and positioningAdherence barriers and mitigationLesson 5Labeling, counseling, and safety: dosing instructions, adverse effect monitoring, measuring devices, and caregiver counselingThis part stresses safe use of kids' liquids with clear labels, right dose guides, caregiver talks, watching bad effects, and using measure tools right to stop errors.
Essential label elements for pediatric liquidsWriting clear, error-resistant directionsSelecting and teaching dosing devicesCaregiver counseling and demonstrationMonitoring adherence and adverse effectsLesson 6Calculation workflows: converting tablet strengths to liquid concentrations and calculating beyond‑use quantities and unit dosesThis part builds math steps for quick kids' liquids, changing tablet power to liquid strength, batch sizes, use-by amounts, and right single doses.
Defining target concentration and volumeConverting tablets or capsules to liquidsAlligation and dilution calculationsDetermining batch size and overfillCalculating and labeling unit dosesLesson 7Excipients for oral pediatric liquids: vehicles, suspending agents, sweeteners, preservatives, buffers, and thickening agents (roles and safety limits)This part reviews fillers for kids' liquids like carriers, thickeners, sweets, germ killers, balance agents, thick stuff, their jobs, usual amounts, safety limits, and age rules.
Aqueous vehicles and cosolvent systemsSuspending and viscosity-building agentsSweeteners and flavoring for palatabilityPreservatives, buffers, and antioxidantsAge-related excipient safety concernsLesson 8Active pharmaceutical ingredient (API) properties: solubility, stability, taste masking, and pKa effects on formulationThis part checks how dissolving, lasting, taste hiding, and acid-base of main drugs affect kids' liquid making, guiding carriers, pH change, taste cover, and shakes or clears.
Aqueous solubility and biopharmaceutic impactpKa, ionization, and pH adjustment strategiesChemical and physical stability in liquid mediaTaste, odor, and bitterness masking optionsChoosing solution vs suspension from API traits
