Crystallization Course
This course equips you with practical skills to master crystallization of organic APIs. You will learn solvent selection, seeding techniques, cooling profiles, PAT implementation, and reliable scale-up strategies. Design robust processes that ensure control over crystal size, polymorphs, filtration, and drying for consistent high-quality batches in pharmaceutical production.

from 4 to 360h flexible workload
valid certificate in your country
What will I learn?
Gain hands-on tools to build strong crystallization processes for organic APIs. Master key concepts like polymorphism, solubility, supersaturation, cooling strategies, seeding, and solvent choices. Explore mixing effects, hydrodynamics, PAT tools, and data-driven methods to control crystal size, filtration, drying, and batch uniformity. Get expert tips on lab experiments, risk evaluation, and smooth scale-up from lab to production.
Elevify advantages
Develop skills
- Design crystallization processes by tuning solubility, supersaturation, and crystal habit quickly.
- Engineer crystal size through optimized cooling, seeding, and mixing for tight particle distribution.
- Control polymorphs using solvents, antisolvents, and solid form risk management.
- Apply PAT tools like FBRM, turbidity, and spectroscopy for real-time process control.
- Scale up robustly by linking lab experiments, hydrodynamics, and risk analysis to plant operations.
Suggested summary
Before starting, you can change the chapters and workload. Choose which chapter to start with. Add or remove chapters. Increase or decrease the course workload.What our students say
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