Lesson 1Infectious disease evaluation: latent infections (TB, CMV, EBV, VZV, HBV, HCV, HIV), vaccination review, prophylaxis planningCovers infection checks for transplant hopefuls, stressing hidden infections, jab status, and custom prevention plans to cut down post-transplant infections and wake-ups under immune suppression.
Screening for TB, CMV, EBV, and VZVHBV, HCV, and HIV testing and stagingPre‑transplant vaccination catch‑up planDonor‑recipient serostatus risk matchingDesigning antiviral and PCP prophylaxisLesson 2Cardiology workup: noninvasive ischemia testing, coronary angiography indications, functional capacity assessment, perioperative revascularization criteriaLooks at heart checks for transplant candidates, covering non-invasive lack-of-blood tests, when to do artery scans, fitness checks, and rules for fixing blockages to lower heart risks during surgery.
Baseline ECG and echocardiographyStress testing and ischemia detectionIndications for coronary angiographyFunctional capacity and METs assessmentRevascularization versus medical therapyLesson 3Endocrine and metabolic optimization: diabetes control strategies pre-transplant, obesity and nutritional optimization, weight-loss options and timelineGoes over hormone and body chemistry fixes before kidney transplant, zeroing in on sugar control, weight and food tweaks, slim-down plans, and real timelines to hit goals that cut surgery and long-term woes.
Pre‑transplant HbA1c and glycemic targetsAdjusting insulin and non‑insulin therapiesObesity‑related surgical and graft risksNutritional assessment and protein‑energy statusPharmacologic and surgical weight‑loss optionsLesson 4Laboratory and imaging baseline tests: crossmatch/serology, HLA typing, PRA, baseline renal ultrasound and vascular imaging, baseline BK/JC viral statusLists key lab and scan tests setting the pre-transplant base, like tissue matching, antibody levels, blood tests, kidney scans, vessel images, and virus checks to steer donor picks and surgery plans.
ABO typing, HLA typing, and PRA levelsComplement‑dependent and flow crossmatchBaseline renal ultrasound and DopplerCT or MR angiography of iliac vesselsBK and JC virus PCR and serologic statusLesson 5Decision criteria to accept or delay transplant: cardiopulmonary thresholds, infection control, vascular access/target vessel suitability, BMI and metabolic targetsShows how teams weigh going ahead or holding off on kidney transplant, mixing heart-lung limits, bug control, vessel fit, and body mass plus body goals to match need with fixable dangers.
Cardiopulmonary fitness and VO2 thresholdsActive infection and sepsis exclusionTarget vessel imaging and suitabilityBMI cutoffs and weight‑loss milestonesMetabolic syndrome and blood pressure goalsLesson 6Pulmonary evaluation and anesthesia risk: spirometry, sleep apnea screening, frailty and functional status assessmentDescribes lung and sleep risk checks, with breath tests, sleep checks, weakness scans, and daily ability reviews to gauge surgery risks and plan fixes, watch, and after-surgery care.
History, exam, and spirometry indicationsChest imaging and pulmonary hypertensionScreening and management of sleep apneaFrailty indices and gait speed testingAnesthesia risk classification and planningLesson 7Vascular surgery assessment: peripheral arterial disease mapping, iliac/femoral vessel duplex/CT angiography, access site planningDives into vessel surgery checks for kidney transplants, mapping leg artery issues, scanning hip and thigh vessels, and picking best entry spots for safe joins and lasting blood flow.
Clinical exam for peripheral arterial diseaseDuplex ultrasound of iliac and femoral vesselsCT angiography for complex vasculatureChoosing side and site for graft anastomosisManaging severe aortoiliac occlusive diseaseLesson 8Hematology and coagulation: platelet function, anticoagulation/antiplatelet management, transfusion thresholdsSpotlights blood and clotting checks, covering low blood counts, clot drug handling, and blood top-up limits to cut bleeding and clot risks around operations.
Baseline CBC, iron studies, and anemia planPlatelet count, function, and uremic bleedingWarfarin, DOAC, and heparin bridgingAntiplatelet interruption and continuationRed cell and platelet transfusion thresholdsLesson 9Psychosocial and adherence assessment: evaluation of social support, substance use, medication adherence predictorsHandles planned social and mind checks before transplant, covering support nets, head health, habit use, and pill-stick forecasts to spot blocks and craft fixes for better graft life.
Standardized psychosocial screening toolsEvaluating caregiver and social supportScreening for depression and anxietySubstance use history and toxicology testsPredictors and remediation of nonadherenceLesson 10Comprehensive medical history and physical exam: diabetes, cardiovascular, peripheral vascular disease, dialysis access reviewSums up full pre-transplant history and body checks, stressing heart, leg vessels, sugar issues, and dialysis line reviews to find no-gos and fixable surgery risks.
Structured transplant‑focused historyCardiovascular and peripheral vascular reviewDiabetes complications and foot examinationDialysis access function and infection historyMedication reconciliation and allergy review
