Crystallization Course
Master the art of crystallizing organic active pharmaceutical ingredients using proven methods for selecting solvents, applying seeding, optimizing cooling curves, implementing PAT, and achieving seamless scale-up. Develop strong processes that precisely manage crystal dimensions, polymorph stability, filtration efficiency, and drying outcomes to deliver uniform, superior-quality batches every time. This comprehensive training ensures reliable production from lab to manufacturing plant.

from 4 to 360h flexible workload
valid certificate in your country
What will I learn?
This course equips you with essential techniques to create dependable crystallization processes for organic APIs. You will explore polymorphism, solubility, supersaturation, cooling strategies, seeding methods, and solvent choices. Gain expertise in mixing effects, hydrodynamics, PAT tools, and data analytics to regulate crystal size, enhance filtration, improve drying, and ensure batch uniformity, including practical experimentation, risk evaluation, and effective scale-up procedures.
Elevify advantages
Develop skills
- Design effective crystallization by adjusting solubility, supersaturation, and crystal shape quickly.
- Engineer precise crystal sizes through optimized cooling, seeding, and mixing for uniform distribution.
- Control polymorph formation using solvent management, antisolvents, and solid form risk mitigation.
- Implement PAT instruments like FBRM, turbidity probes, and spectroscopy for live process monitoring.
- Scale up confidently by integrating lab experiments, hydrodynamics, and risk assessments with production runs.
Suggested summary
Before starting, you can change the chapters and workload. Choose which chapter to start with. Add or remove chapters. Increase or decrease the course workload.What our students say
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