Lesson 1Infectious disease evaluation: latent infections (TB, CMV, EBV, VZV, HBV, HCV, HIV), vaccination review, prophylaxis planningDis part explain infection disease check for transplant candidates, stressing hidden infections, vaccine status, and personal prophylaxis plans to cut down post-transplant chance infections and wake-up under immune suppression.
Screening for TB, CMV, EBV, and VZVHBV, HCV, and HIV testing and stagingPre‑transplant vaccination catch‑up planDonor‑recipient serostatus risk matchingDesigning antiviral and PCP prophylaxisLesson 2Cardiology workup: noninvasive ischemia testing, coronary angiography indications, functional capacity assessment, perioperative revascularization criteriaCover heart check for transplant candidates, including noninvasive ischemia test, when to do coronary angiography, check functional capacity, and rules for revascularization to reduce heart problems during operation.
Baseline ECG and echocardiographyStress testing and ischemia detectionIndications for coronary angiographyFunctional capacity and METs assessmentRevascularization versus medical therapyLesson 3Endocrine and metabolic optimization: diabetes control strategies pre-transplant, obesity and nutritional optimization, weight-loss options and timelineLook at hormone and metabolic issues before kidney transplant, focusing diabetes fix, obesity and food, weight loss ways, and real time plans to hit metabolic goals dat reduce operation and long-term problems.
Pre‑transplant HbA1c and glycemic targetsAdjusting insulin and non‑insulin therapiesObesity‑related surgical and graft risksNutritional assessment and protein‑energy statusPharmacologic and surgical weight‑loss optionsLesson 4Laboratory and imaging baseline tests: crossmatch/serology, HLA typing, PRA, baseline renal ultrasound and vascular imaging, baseline BK/JC viral statusOutline key lab and imaging tests dat set pre-transplant base, including HLA typing, PRA, crossmatch, blood tests, kidney ultrasound, vessel imaging, and BK/JC virus status to guide donor pick and operation planning.
ABO typing, HLA typing, and PRA levelsComplement‑dependent and flow crossmatchBaseline renal ultrasound and DopplerCT or MR angiography of iliac vesselsBK and JC virus PCR and serologic statusLesson 5Decision criteria to accept or delay transplant: cardiopulmonary thresholds, infection control, vascular access/target vessel suitability, BMI and metabolic targetsExplain how team decide to go ahead or hold kidney transplant, mixing heart-lung limits, infection control, vessel fit, and BMI metabolic goals to balance hurry against fixable risks.
Cardiopulmonary fitness and VO2 thresholdsActive infection and sepsis exclusionTarget vessel imaging and suitabilityBMI cutoffs and weight‑loss milestonesMetabolic syndrome and blood pressure goalsLesson 6Pulmonary evaluation and anesthesia risk: spirometry, sleep apnea screening, frailty and functional status assessmentDescribe lung and anesthesia risk check, including spirometry, sleep apnea screen, frailty, and function status, to guess operation risk and guide fix, watch, and after-operation plans.
History, exam, and spirometry indicationsChest imaging and pulmonary hypertensionScreening and management of sleep apneaFrailty indices and gait speed testingAnesthesia risk classification and planningLesson 7Vascular surgery assessment: peripheral arterial disease mapping, iliac/femoral vessel duplex/CT angiography, access site planningLook into vessel surgery check for kidney transplant plan, including mapping leg artery disease, imaging iliac and femoral vessels, and picking best access spots to make safe join and long-term graft blood flow.
Clinical exam for peripheral arterial diseaseDuplex ultrasound of iliac and femoral vesselsCT angiography for complex vasculatureChoosing side and site for graft anastomosisManaging severe aortoiliac occlusive diseaseLesson 8Hematology and coagulation: platelet function, anticoagulation/antiplatelet management, transfusion thresholdsFocus on blood and clotting check, including anemia, platelet work, and handling blood thinners and antiplatelet meds, to set transfusion limits and cut bleeding and clotting around surgery.
Baseline CBC, iron studies, and anemia planPlatelet count, function, and uremic bleedingWarfarin, DOAC, and heparin bridgingAntiplatelet interruption and continuationRed cell and platelet transfusion thresholdsLesson 9Psychosocial and adherence assessment: evaluation of social support, substance use, medication adherence predictorsCover proper psychosocial check before transplant, including social help, mental health, substance use, and signs of med sticking, to find blocks and make plans dat improve long-term graft life.
Standardized psychosocial screening toolsEvaluating caregiver and social supportScreening for depression and anxietySubstance use history and toxicology testsPredictors and remediation of nonadherenceLesson 10Comprehensive medical history and physical exam: diabetes, cardiovascular, peripheral vascular disease, dialysis access reviewSum up full pre-transplant history and physical check, stressing heart vessel, leg vessel, diabetes, and dialysis access review to find no-go and fixable operation risks.
Structured transplant‑focused historyCardiovascular and peripheral vascular reviewDiabetes complications and foot examinationDialysis access function and infection historyMedication reconciliation and allergy review
