Lesson 1Compounding procedures for oral liquids: wetting, triturating, levigating, and homogenization techniques; equipment and in‑process controlsThis part dey describe step by step mixing of pickin mouth liquids, including calculations, grinding, wetting, levigating, diluting, homogenizing, filtering, and checks during process to make sure even, stable, and no germ.
Pre-compounding checks and calculationsTrituration, wetting, and levigation stepsOrder of mixing and volume make-upHomogenization and de-aeration methodsIn-process controls and documentationLesson 2Stability, beyond‑use dating, storage, and transport for pediatric liquids; container selection and oral dosing devicesThis part dey detail stability things for pickin liquids, like breakdown paths, germ risks, beyond-use date, and how container, cover, storage, transport affect quality, safety, and dose sure thing.
Degradation pathways in aqueous preparationsMicrobial growth risks and preservative needsAssigning evidence-based beyond-use datesContainer and closure selection criteriaStorage, transport, and temperature controlLesson 3Selection of dosage form: solution vs suspension vs syrup — advantages and limitationsThis part dey compare solutions, suspensions, syrups for pickin, outlining good sides, limits, and pick criteria from drug properties, dose flex, stability, taste like, and error risk.
Characteristics of oral solutionsCharacteristics of oral suspensionsCharacteristics of syrups and elixirsComparing stability and dose uniformityChoosing dosage form for specific APIsLesson 4Clinical considerations for pediatric patients: dosing by weight, formulation acceptability, and administration aidsThis part dey handle clinic sides of pickin therapy with mouth liquids, including weight dose, age right volume, if formulation good, help tools, and ways to make dem follow and less mistake.
Weight- and BSA-based dose calculationsAge-appropriate dosing volumesAssessing taste and texture acceptabilityAdministration aids and positioningAdherence barriers and mitigationLesson 5Labeling, counseling, and safety: dosing instructions, adverse effect monitoring, measuring devices, and caregiver counselingThis part dey focus on safe use of pickin liquids with clear label, right dose words, caregiver talk, and watch for bad effects, stressing no error and correct measure tools.
Essential label elements for pediatric liquidsWriting clear, error-resistant directionsSelecting and teaching dosing devicesCaregiver counseling and demonstrationMonitoring adherence and adverse effectsLesson 6Calculation workflows: converting tablet strengths to liquid concentrations and calculating beyond‑use quantities and unit dosesThis part dey build calculation flows for quick pickin liquids, covering change solid strength to target mix, find batch size, beyond-use amount, and right unit dose volume.
Defining target concentration and volumeConverting tablets or capsules to liquidsAlligation and dilution calculationsDetermining batch size and overfillCalculating and labeling unit dosesLesson 7Excipients for oral pediatric liquids: vehicles, suspending agents, sweeteners, preservatives, buffers, and thickening agents (roles and safety limits)This part dey check excipients for pickin liquids, like carriers, suspenders, sweetners, preservatives, buffers, thickeners, showing work, usual strength, safety limits, age no-go.
Aqueous vehicles and cosolvent systemsSuspending and viscosity-building agentsSweeteners and flavoring for palatabilityPreservatives, buffers, and antioxidantsAge-related excipient safety concernsLesson 8Active pharmaceutical ingredient (API) properties: solubility, stability, taste masking, and pKa effects on formulationThis part dey look how dissolve, pKa, stability, taste of APIs affect pickin liquid design, guiding carrier pick, pH change, taste hide ways, need suspend or solution.
Aqueous solubility and biopharmaceutic impactpKa, ionization, and pH adjustment strategiesChemical and physical stability in liquid mediaTaste, odor, and bitterness masking optionsChoosing solution vs suspension from API traits
