Lesson 1Documentation and use of prior medical records and imaging to establish dissemination in time or exclude previous eventsDis section cover how fi get, check, an write down prior medical records an imaging fi establish dissemination in time, confirm earlier demyelinating events, or find competing diagnoses dat might change di workin MS diagnosis, real talk.
Locating and requesting historical recordsReviewing prior neurological documentationComparing historical and current MRI studiesIdentifying earlier demyelinating eventsReconciling conflicting prior diagnosesLesson 2Structured neurological history for demyelinating disease (onset patterns, relapse characterization, timing, prior transient events, red flags)Dis section explain how fi tek a structured neurological history in suspected demyelinating disease, focusin pon onset patterns, relapse characterization, timin, prior transient events, exposures, an red flags dat may indicate non-MS conditions, yuh haffi watch dat.
Characterizing symptom onset and evolutionDetailing relapses and recovery patternsEliciting prior transient neurological eventsMedication, infection, and vaccine historyScreening for systemic and red-flag symptomsLesson 3Baseline laboratory tests to exclude mimics (infectious, metabolic, inflammatory, vitamin deficiencies, autoimmune serology including AQP4 and MOG antibodies)Dis section outline baseline laboratory tests used fi exclude MS mimics, includin infectious, metabolic, inflammatory, an nutritional causes, an review autoimmune serology such as AQP4 an MOG antibodies in demyelinating disorders, check it proper.
Core metabolic and hematologic screeningInfectious evaluations relevant to MS mimicsVitamin and nutritional deficiency testingAutoimmune serology including AQP4 and MOGInterpreting abnormal labs in contextLesson 4Essential baseline investigations: MRI brain and spinal cord protocols and reporting elements (sequences, lesion location, dissemination in space/time markers)Dis section describe essential MRI brain an spinal cord protocols in MS, includin recommended sequences, lesion locations, an reportin elements, an explain radiologic markers of dissemination in space an time fi diagnostic classification, seen.
Core brain MRI sequences for MSSpinal cord MRI indications and techniqueTypical MS lesion locations and patternsGadolinium use and dissemination in timeStandardized MRI reporting elementsLesson 5Red-flag symptoms and signs that suggest alternative diagnoses (rapid progression, fever, systemic features)Dis section identify clinical red flags dat argue against MS, such as rapid progression, fever, systemic features, or prominent peripheral involvement, an explain how fi adjust di diagnostic workup when alternative diagnoses are suspected, nuh play.
Atypical onset and rapid progressionSystemic symptoms and constitutional signsPeripheral nervous system and pain red flagsImaging and CSF features against MSEscalating evaluation for alternative causesLesson 6Role and interpretation of cerebrospinal fluid testing (oligoclonal bands, IgG index, opening pressure, cell count)Dis section review key cerebrospinal fluid parameters in suspected MS, includin oligoclonal bands, IgG index, cell count, an openin pressure, an explain how fi interpret patterns dat support MS or suggest alternative diagnoses, yuh get me.
CSF collection, handling, and contraindicationsOligoclonal bands and IgG index interpretationCSF cell count, protein, and opening pressureCSF patterns suggesting alternative diagnosesIntegrating CSF with MRI and clinical dataLesson 7How to synthesize clinical and paraclinical data into a diagnostic timeline (first event, subsequent events, asymptomatic lesions)Dis section teach how fi synthesize clinical attacks, MRI, CSF, an ancillary tests into a coherent diagnostic timeline, distinguishin first events, relapses, an asymptomatic lesions fi determine whether MS criteria are fulfilled, lock in.
Defining clinical attacks and relapsesClassifying asymptomatic MRI lesionsAligning clinical events with imagingApplying dissemination in space and timeCommunicating the diagnostic timelineLesson 8Use and limits of evoked potentials (visual, somatosensory, brainstem auditory) in diagnosis and subclinical lesion detectionDis section explain indications, techniques, an interpretation of visual, somatosensory, an brainstem auditory evoked potentials in MS, highlightin dem role in detectin subclinical lesions an dem limitations in modern diagnostic criteria, irie.
Physiologic basis of evoked potentialsVisual evoked potentials in optic pathway diseaseSomatosensory and brainstem auditory studiesSensitivity, specificity, and technical pitfallsWhen evoked potentials change managementLesson 9Targeted neurological examination for optic neuritis, myelopathy, cerebellar and cognitive dysfunctionDis section detail a focused neurological examination fi suspected MS, emphasizin bedside assessment of optic neuritis, myelopathy, cerebellar dysfunction, an cognitive changes, an how fi document findins dat support dissemination in space, yuh haffi do it right.
Bedside assessment of optic neuritisExamining long tracts in suspected myelopathyCerebellar signs and gait assessmentScreening bedside cognitive evaluationSummarizing exam findings by functional system
