Lesson 1Psychosocial and adherence assessment: evaluation of social support, substance use, medication adherence predictorsCovers planned social and mental health checks before transplant, including family support, mind health, drug or alcohol use, and signs of sticking to meds, to spot barriers and plan fixes for better long-term kidney survival.
Standardized psychosocial screening toolsEvaluating caregiver and social supportScreening for depression and anxietySubstance use history and toxicology testsPredictors and remediation of nonadherenceLesson 2Comprehensive medical history and physical exam: diabetes, cardiovascular, peripheral vascular disease, dialysis access reviewSums up how to do a full pre-transplant history and body check, stressing heart, leg vessels, diabetes, and dialysis line review to find no-go factors and fixable surgery risks.
Structured transplant‑focused historyCardiovascular and peripheral vascular reviewDiabetes complications and foot examinationDialysis access function and infection historyMedication reconciliation and allergy reviewLesson 3Hematology and coagulation: platelet function, anticoagulation/antiplatelet management, transfusion thresholdsFocuses on blood and clotting checks, covering anaemia, platelet work, handling blood thinners and anti-clot drugs, setting blood transfusion limits, and cutting bleeding and clotting risks around surgery.
Baseline CBC, iron studies, and anemia planPlatelet count, function, and uremic bleedingWarfarin, DOAC, and heparin bridgingAntiplatelet interruption and continuationRed cell and platelet transfusion thresholdsLesson 4Vascular surgery assessment: peripheral arterial disease mapping, iliac/femoral vessel duplex/CT angiography, access site planningLooks into vessel surgery checks for kidney transplant planning, mapping leg artery problems, scanning iliac and femoral vessels, and picking best entry points for safe joining and long-term kidney blood flow.
Clinical exam for peripheral arterial diseaseDuplex ultrasound of iliac and femoral vesselsCT angiography for complex vasculatureChoosing side and site for graft anastomosisManaging severe aortoiliac occlusive diseaseLesson 5Pulmonary evaluation and anesthesia risk: spirometry, sleep apnea screening, frailty and functional status assessmentDescribes lung and anaesthesia risk checks, including breathing tests, sleep apnoea screening, weakness levels, and daily function checks, to gauge surgery risks and plan improvements, watching, and after-surgery care.
History, exam, and spirometry indicationsChest imaging and pulmonary hypertensionScreening and management of sleep apneaFrailty indices and gait speed testingAnesthesia risk classification and planningLesson 6Infectious disease evaluation: latent infections (TB, CMV, EBV, VZV, HBV, HCV, HIV), vaccination review, prophylaxis planningLooks at infection checks for transplant candidates, focusing on hidden infections, vaccine status, and custom plans to prevent infections after transplant when the body is weakened by drugs.
Screening for TB, CMV, EBV, and VZVHBV, HCV, and HIV testing and stagingPre‑transplant vaccination catch‑up planDonor‑recipient serostatus risk matchingDesigning antiviral and PCP prophylaxisLesson 7Cardiology workup: noninvasive ischemia testing, coronary angiography indications, functional capacity assessment, perioperative revascularization criteriaDeals with heart checks for transplant candidates, including non-invasive tests for blocked blood flow, when to do heart vessel scans, checking physical ability, and rules for fixing blood vessels to cut down heart problems during surgery.
Baseline ECG and echocardiographyStress testing and ischemia detectionIndications for coronary angiographyFunctional capacity and METs assessmentRevascularization versus medical therapyLesson 8Endocrine and metabolic optimization: diabetes control strategies pre-transplant, obesity and nutritional optimization, weight-loss options and timelineGoes over hormone and body chemistry issues before kidney transplant, stressing diabetes control, handling obesity and food needs, weight loss methods, and real timelines to hit targets that lower surgery and long-term issues.
Pre‑transplant HbA1c and glycemic targetsAdjusting insulin and non‑insulin therapiesObesity‑related surgical and graft risksNutritional assessment and protein‑energy statusPharmacologic and surgical weight‑loss optionsLesson 9Laboratory and imaging baseline tests: crossmatch/serology, HLA typing, PRA, baseline renal ultrasound and vascular imaging, baseline BK/JC viral statusSets out key lab and scan tests that establish the starting point before transplant, like HLA typing, PRA, crossmatch, blood tests, kidney ultrasound, vessel scans, and BK/JC virus checks to help pick donors and plan surgery.
ABO typing, HLA typing, and PRA levelsComplement‑dependent and flow crossmatchBaseline renal ultrasound and DopplerCT or MR angiography of iliac vesselsBK and JC virus PCR and serologic statusLesson 10Decision criteria to accept or delay transplant: cardiopulmonary thresholds, infection control, vascular access/target vessel suitability, BMI and metabolic targetsExplains how teams from different fields decide to go ahead or wait on kidney transplant, weighing heart and lung limits, infection handling, vessel fitness, and BMI and body goals to match urgency with fixable risks.
Cardiopulmonary fitness and VO2 thresholdsActive infection and sepsis exclusionTarget vessel imaging and suitabilityBMI cutoffs and weight‑loss milestonesMetabolic syndrome and blood pressure goals
