Genomics Course
This course offers a comprehensive, hands-on introduction to whole-exome sequencing (WES) analysis for identifying rare genetic disorders in families, covering the full pipeline from data processing to clinical reporting with a focus on inherited cancer risks.

flexible workload of 4 to 360h
valid certificate in your country
What will I learn?
This Genomics Course provides a practical, complete workflow for whole-exome sequencing in rare family disorders. Learn study design, raw data quality checks, alignment, variant calling, and joint genotyping using current best practices. Gain hands-on skills in annotation, population frequency filtering, variant prioritisation, validation, and clinical reporting, with clear examples focused on inherited cancer risks.
Elevify advantages
Develop skills
- WES study design: plan small family exome projects for rare inherited diseases.
- Read alignment & QC: align WES reads, check quality, and fix common issues.
- Variant calling & filtering: run inherited variant callers and adjust thresholds for clean VCF files.
- Annotation & prioritisation: use gnomAD, ClinVar, and computational scores to rank potential variants.
- Clinical interpretation: classify variants using ACMG guidelines and prepare clear reports.
Suggested summary
Before starting, you can change the chapters and the workload. Choose which chapter to start with. Add or remove chapters. Increase or decrease the course workloadWhat our students say
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I like how the lessons get straight to the point and how I can switch chapters and skip content I don't need.

Mariana FerresPhotography Student
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The platform is fast and easy to use. The variety of content and the extra videos really help with learning.

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