Crystallization Course
Master the crystallisation of organic APIs using practical tools for solvent selection, seeding, cooling profiles, PAT, and scale-up. Develop robust processes that control crystal size, polymorphs, filtration, and drying to ensure consistent, high-quality products. This course equips participants with essential techniques for designing reliable manufacturing processes in pharmaceutical production.

4 to 360 hours flexible workload
valid certificate in your country
What will I learn?
This Crystallisation Course provides practical tools to design robust processes for organic active pharmaceutical ingredients (APIs). Participants will gain insights into polymorphism, solubility, and supersaturation, while mastering cooling profiles, seeding, and solvent selection. The course covers mixing, hydrodynamics, process analytical technology (PAT), and data-driven control strategies to influence crystal size, filtration, drying, and batch consistency, with emphasis on experimentation, risk assessment, and dependable scale-up.
Elevify advantages
Develop skills
- Design crystallisation processes by adjusting solubility, supersaturation, and crystal habit efficiently.
- Engineer crystal size through optimised cooling, seeding, and mixing for precise particle size distribution.
- Control polymorphs by managing solvents, antisolvents, and solid form risks effectively.
- Apply PAT tools including FBRM, turbidity, and spectroscopy for real-time process control.
- Scale up reliably by integrating lab DoE, hydrodynamics, and risk analysis with plant operations.
Suggested summary
Before starting, you can change the chapters and the workload. Choose which chapter to start with. Add or remove chapters. Increase or decrease the course workload.What our students say
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