Bio Chemical Engineering Course
Master the art of scaling aerobic E. coli fermentations from lab to production scale, covering design, oxygen transfer, mixing, thermal management, and risk control for successful biochemical engineering.

4 to 360h flexible workload
certificate valid in your country
What will I learn?
This Biochemical Engineering Course provides a practical roadmap to design, control, and scale aerobic E. coli fermentations from 5 L to 5,000 L with confidence. Learn key microbial and recombinant protein fundamentals, oxygen transfer and mixing criteria, heat generation and cooling limits, robust control strategies, and a clear risk assessment and mitigation framework to make sound, data-driven scale-up decisions.
Elevify advantages
Develop skills
- Fermentation design: define E. coli lab processes with realistic growth parameters.
- Oxygen transfer scaling: size kLa and aeration from 5 L to 5,000 L fast.
- Mixing and hydrodynamics: choose impellers, P/V, and limits for shear-sensitive runs.
- Thermal management: estimate heat loads and verify cooling for large bioreactors.
- Scale-up risk control: build go/no-go, mitigation, and documentation frameworks.
Suggested summary
Before starting, you can change the chapters and the workload. Choose which chapter to start with. Add or remove chapters. Increase or decrease the course workload.What our students say
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